Search results for " pemphigus vulgaris"
showing 3 items of 3 documents
Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review
2021
Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, pre…
CEFACLOR INDUCED PEMPHIGUS VULGARIS
2004
Pemphigus is a chronic disease with an outcome that is not without risk. It is characterised by loss of the intraepithelial cell-cell relationship (acantholysis). Underlying the disease is an autoimmune disorder in which the desmosomes are damaged by antibodies directed against particular molecules called desmogleins (particularly 3 and 1). Various types of pemphigus have been described with different antibody profiles and clinical signs. In the present paper, a case of pemphigus vulgaris associated with the medication cefaclor monohydrate is reported. Histological and immunological evaluation of the biopsy sample led to a diagnosis of pemphigus vulgaris. The patient, who was not hospitalis…
Mycophenolate mofetil and enteric-coated mycophenolate sodium in the treatment of pemphigus vulgaris and pemphigus foliaceus.
2014
What is known and objective: Pemphigus is a severe, potentially life-threatening autoimmune blistering disease. The use of corticosteroids has dramatically improved the prognosis and changed its course. However, current morbidity of pemphigus is largely iatrogenic, caused by side effects of the long-term, high-dose corticosteroid therapy that is necessary to sustain disease control. In order to minimize side effects, a range of corticosteroid-sparing immunosuppressive agents have been introduced, including mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS). A systematic review was performed to evaluate the effectiveness of MMF and EC-MPS in the treatment of pemphig…